Coagulation factor levels in solvent/detergent-treated plasma
نویسندگان
چکیده
منابع مشابه
Coagulation factor levels in solvent/detergent-treated plasma.
Recently, an extensive committee report on the current status of solvent/detergent (S/D)-treated frozen plasma was published by Klein et al.1 in TRANSFUSION. Although S/Dtreated plasma is now widely used, little is published about the amount and the stability of the individual coagulation factors in S/D-treated plasma.2,3 According to the manufacturers, S/D treatment does not significantly alte...
متن کاملMice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels
Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVIII) in plasma. It has been reported that the infusion of FVIII concentrate in haemophilia A patients results in lowered VWF plasma levels. However, the impact of F8-deficiency on VWF plasma levels in F8-/y mice is unresolved. In order to avoid confounding variables, we back-crossed F8-deficient mice onto ...
متن کاملEvidence Suggesting the Regulation of Coagulation Factor Levels in Rabbits by a Transferable Plasma Agent
New Zealand white rabbits were given 30 ml of goat serum intravenously. This procedure resulted in an immediate decrease in platelet count, fibrinogen, and levels of coagulation factors II, V, VII, and x, due to consumption coagulopathy. These factors returned toward baseline levels approximately 1 2 hr after the injection. Plasma from rabbits who had received goat serum 48 hr previously ( dono...
متن کاملEvidence suggesting the regulation of a coagulation factor levels in rabbits by a transferable plasma agent.
New Zealand white rabbits were given 30 ml of goat serum intravenously. This procedure resulted in an immediate decrease in platelet count, fibrinogen, and levels of coagulation factors II, V, VII, and X, due to consumption coagulopathy. These factors returned toward baseline levels approximately 12 hr after the injection. Plasma from rabbits who had received goat serum 48 hr previously (donor ...
متن کاملDevelopment of aptameric affinity ligands specific to human plasma coagulation factor VIII using SEC-SELEX
Protein specific aptamers are highly applicable affinity ligands in different fields of research and clinical applications. They have been developed against various targets, in particular, bio-macromolecules such as proteins. Among human proteins, the coagulation factors are the most attractive targets for aptamer selection and their specific aptamers had valuable characteristics in therapeutic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Transfusion
سال: 1999
ISSN: 0041-1132,1537-2995
DOI: 10.1046/j.1537-2995.1999.39101150.x